Patient's suffering goes beyond the attacks

  • HAE attacks are a considerable burden for those affected, making everyday life more difficult and causing absences from school and work.
  • HAE attacks pose a significant burden on those affected, complicating daily life and leading to absences from school and work. Patients with Hereditary Angioedema live with a constant fear of impending attacks that persist throughout their lifetime1

Impact of QoL before, during and between the attacks1-4

physical phychological

LANADELUMAB 300 mg every 2 weeks increased patients' chances of improvement in quality of life by‘

a 7.2 times greater likelihood of improvement vs placebo (odds ratio: 7.2; P=0.001)7

Patients-reported outcomes and quality of life6

(HELP study)

  1. In the HELP Study, combined patients across all lanadelumab treatment groups showed significant reductions in AE-QoL total score and all domain scores (functioning, fatigue/mood, fear/shame, and nutrition) compared with placebo.
  2. The largest improvement across all AE-QoL domainscores was observed in the functioning domain5

Every attack is one too many!

The psychological suffering associated with hereditary angioedema (HAE) can often go unnoticed. Tools like the Angioedema Control Test (AECT) and Angioedema Quality of Life Questionnaire (AE-QoL) provide valuable insights into patients' well-being.
Learn more about these tools here.8,9

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